金沢大学 薬物動態学研究室

Achievement 2011: Regular articles

  1. Imanaga J., Kotegawa T, Imai H, Tsutsumi K, Yoshizato T, Ohyama T, Shirasaka Y, Tamai I, Tateishi T, Ohashi K. The effects of the SLCO2B1 c.1457C>T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans. Pharmacogenet Genomics, 21: 84-93 (2011).
  2. Sato M, Wakayama T, Mamada H, Shirasaka Y, Nakanishi T, Tamai I. Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats. Biochim Biophys Acta, 1808: 1441-1447 (2011).
  3. Kato K, Shirasaka Y, Kuraoka E, Kikuchi A, Iguchi M, Suzuki H, Shibasaki S, Kurosawa T, Tamai I. Intestinal absorption mechanism of tebipenem pivoxil, a novel oral carbapenem: Involvement of human OATP family in apical membrane transport. Mol Pharm, 7: 1747-1756 (2011).
  4. Shirasaka Y, Suzuki K, Shichiri M, Nakanishi T, Tamai I. Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. Drug Metab Pharmacokinet, 26: 171-179 (2011).
  5. Saheki A, Fukui Y, Hoshi Y, Fukui H, Seki J, Tamai I. Influence of preparation method on polynucleotide conformation and pharmacological activity of lipoplex. Int J Pharm, 406: 117-121 (2011).
  6. Mizutani M, Inagaki F, Nakanishi T, Yanagihara C, Tamai I. Mukai C. Total syntheses of (-) - and (+)- goniomitine. Org Lett, 13: 1796-1799 (2011).
  7. Nakanishi T, Shibue Y, Fukuyama Y, Yoshida K, Fukuda H, Shirasaka Y, Tamai I. Quantitative time-lapse imaging (QTLI)-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug associated protein 2, in sandwich-cultured rat hepatocytes. Drug Metab Dispos, 39: 984-991 (2011).
  8. Okudaira H, Shikano N, Nishii R, Miyagi T, Yoshimoto M, Kobayashi M, Ohe K, Nakanishi T, Tamai I, Namiki M, Kawai K. Putative transport mechanism and intracellular fate of anti-18F-FACBC (trans-1-amino-18F-fluorocyclobutanecarboxylic acid) in human prostate cancer. J Nucl Med, 52: 822-829 (2011).
  9. Shirasaka Y, Suzuki K, Nakanishi T, Tamai I. Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. J Pharm Sci, 100: 3843-3853 (2011).
  10. Morimoto K, Kishimura K, Nagami T, Kodama N, Ogama Y, Yokoyama M, Toda S, Chiyoda T, Shimada R, Inano A, Kano T, Tamai I, Ogihara T. Effect of milk on the pharmacokinetics of oseltamivir in healthy volunteers. J Pharm Sci, 100: 3854-3861 (2011).
  11. Jong NN, Nakanishi T, Liu JJ, Tamai I, McKeage MJ. Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons. J Pharmacol Exp Ther, 338: 537-547 (2011).
  12. Nakanishi T, Fukushi A, Sato M, Yoshifuji M, Gose T, Shirasaka Y, Ohe K, Kobayashi M, Kawai K, Tamai I. Functional characterization of apical transporters expressed in rat proximal tubular cells (PTCs) in primary culture. Mol Pharm, 8: 2142-2150 (2011).
  13. Hou X, Huang F, Carboni JM, Flatten K, Asmann YW, Ten Eyck C. Nakanishi T, Tibodeau JD, Ross DD, Gottardis MM, Erlicman C, Kaufmann S, Haluska P. Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazoles insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. Mol Cancer Ther, 10(1): 117-125 (2011).
  14. Natarajan K, Xie Y, Nakanishi T, Beck WT, Bauer KS, Ross DD. Identification and characterization of the major alternatie promoter regulating Bcrp/Abcg2 expression in the mouse intestine. Biochem Biophys Acta, 1809(7): 295-305 (2011).
  15. Nakanishi T, Fukuyama Y, Fujita M, Shirasaka Y, Tamai I. Carnitine precursor γ-butyrobetaine is a novel substrate of the Na+- and Cl--dependent GABA transporter Gat2. Drug Metab Pharmacokinet, 26(6): 632-636 (2011).

2018 International Meeting on 22nd MDO and 33rd JSSX

第39回生体膜と薬物の相互作用シンポジウム

薬物動態学研究室
〒920-1192
石川県金沢市角間町