Achievement 2016: Regular Articles

1. Takeuchi R, Shinozaki K, Nakanishi T, Tamai I. Local drug-drug interaction of donepezil with cilostazol at breast cancer resistance protein (ABCG2) increases drug accumulation in heart. Drug Metab Dispos, 44(1): 68-74 (2016).
2. Fujita D, Saito Y, Nakanishi T, Tamai I. Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of CPT-11. Drug Metab Dispos, 44(1): 1-7 (2016).
3. Matsunaga N, Kaneko N, Staub AY, Nakanishi T, Nunoya KI, Imawaka H, Tamai I. Analysis of metabolic pathway of bosentan and cytotoxicity of bosentan metabolites based on a quantitative modeling of metabolism and transport in sandwich-cultured human hepatocytes. Drug Metab Dispos, 44(1): 16-27 (2016).
4. Incecayir T, Sun J, Tsume Y, Xu Hao, Gose T, Nakanishi T, Tamai I, Hilfinger J, Lipka E, Amidon GL. Carrier-mediated prodrug uptake to improve the oral bioavailability of polar drugs: an application to an oseltamivir analogue. J Pharm Sci, 105(2): 925-34 (2016).
5. Kasai T, Nakanishi T, Ohno Y, Shimada H, Nakamura Y, Arakawa H, Tamai I. Role of OATP2A1 in PGE₂ secretion from human colorectal cancer cells via exocytosis in response to oxidative stress. Exp Cell Res, 341 (2): 123-131 (2016).
6. Hoshino Y, Fujita D, Nakanishi T, Ikumi Tamai. Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug-drug interaction. Medchemcomm, 7: 1775-1782 (2016)
7. Gose T, Nakanishi T, Kamo S, Shimada H, Otake K, Tamai I. Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicoapentanoic acid-derived PGE₃. Prostaglandins Other Lipid Mediat, 122:10-17 (2016).
8. Saito Y, Kumamoto T, Makino Y, Tamai I, Ogawa C, Terakado H. A retrospective study of treatment and prophylaxis of ifosfamide-induced hemorrhagic cystitis in pediatric and adolescent and young adult (AYA) patients with solid tumors. Jpn J Clin Oncol, 46(9): 856-861 (2016).