Achievement 2019: Regular articles

1. Nakanishi T, Takashima H, Uetoko Y, Komori H, Tamai I. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport. J. Pharmacol. Exp. Ther., 368(2), 317-325 (2019).

2. Washio I, Nakanishi T, Ishiguro N, Bister B, Tamai I. Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines. Biopharm. Drug Dispos., 40(1): 32-43 (2019).

3. Arakawa H, Amezawa N, Katsuyama T, Nakanishi T, Tamai I. Uric acid analogue as a possible xenobiotic marker of uric acid transporter Urat1 in rats. Drug Metab. Pharmacokinet., 34(2): 155-158 (2019).

4. Nishizawa K, Yoda N, Morokado F, Komori H, Nakanishi T, Tamai I. Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia. PLoS One, 14(4):e0214862 (2019).

5. Arakawa H, Kubo H, Washio I, Staub AY, Nedachi S, Ishiguro N, Nakanishi T, Tamai I. Rat Kidney Slices for Evaluation of Apical Membrane Transporters in Proximal Tubular Cells. J. Pharm. Sci., S0022-3549(19)30215-1 (2019).

6. Myint K, Biswas R, Li Y, Jong N, Jamieson S, Liu J, Han C, Squire C, Merien F, Lu J, Nakanishi T, Tamai I, McKeage M. Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer. Sci Rep., 19;9(1):2245 (2019).

7. Ishii S, Kitazawa H, Mori T, Kirino A, Nakamura S, Osaki N, Shimotoyodome A, Tamai I. Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice. Sci Rep., 29;9(1):11014 (2019).

8. Kobayashi M, Nishi K, Mizutani A, Hokama T, Matsue M, Tsujikawa T, Nakanishi T, Nishii R, Tamai I, Kawai K. Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol. Sci Rep., 16;9(1):13413 (2019).

9. Motoki K, Igarashi T, Omura K, Nakatani H, Iwanaga T, Tamai I, Ohashi T. Pharmacokinetic/pharmacodynamic modeling and simulation of dotinurad, a novel uricosuric agent, in healthy volunteers. Pharmacol Res Perspect., 26;7(6):e00533 (2019).

10. Koyanagi T, Yano K, Kim S, Murayama N, Yamazaki H, Tamai I. In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys and humans. Xenobiotica., 49(8):887-894 (2019).