金沢大学 薬物動態学研究室

Achievement 2021: Regular articles

1. Zhu Q, Komori H, Imamura R, Tamai I, A Novel Fluorescence-Based Method to Evaluate Ileal Apical Sodium-Dependent Bile Acid Transporter ASBT. , Journal of Pharmaceutical Sciences, 110(3): 1392-1400 (2021).

2. Cai H, Cheng Y, Zhu Q, Kong D, Chen X, Tamai I, Lu Y, Identification of Triterpene Acids in Poria cocos Extract as Bile Acid Uptake Transporter Inhibitors., Drug Metabolism and Disposition, 49(5):353-360 (2021).

3. Kobayashi M, Mizutani A, Okamoto T, Muranaka Y, Nishi K, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K., Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. Nuclear Medicine and Biology, 94-95:92-97 (2021).

4. Arai M, Komori H, Fujita D, Tamai I, Uptake pathway of apple-derived nanoparticle by intestinal cells to deliver its cargo., Pharmaceutical Research, 38(3):523-530 (2021).

5. Nakazono Y, Arakawa H, Nishino M, Yamaki I, Oba T, Tomotoshi K, Kakinuma C, Ogihara T, Tamai I, Drug Transcellular Transport Assay Using a High Porosity Honeycomb Film., Biological and Pharmaceutical Bulletin, 44(5):635-641 (2021).

6. Komori H, Fujita D, Shirasaki Y, Zhu Q, Iwamoto Y, Nakanishi T, Nakajima M, Tamai I, MicroRNAs in apple-derived nanoparticles modulate intestinal expression of OATP2B1/SLCO2B1 in Caco-2 cells., Drug Metabolism and Disposition, 49(9):803-809 (2021).

7. Konno S, Kobayashi K, Senda M, Funai Y, Seki Y, Tamai I, Schäkel L, Sakata K, Pillaiyar T, Taguchi A, Taniguchi A, Gütschow M, E Müller C, Takeuchi K, Hirohama M, Kawaguchi A, Kojima M, Senda T, Shirasaka Y, Kamitani W, Hayashi Y, 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents., Journal of Medicinal Chemistry, 65(4):2926-2939 (2021).


8. Suzuki S, Inoue K, Tamai I, Shirasaka Y, Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme., Pharmaceutical Research, 38(9):1585-1592 (2021).


9. Takemura M, Tanaka Y, Inoue K, Tamai I, Shirasaka Y, Influence of osmolality on gastrointestinal fluid volume and drug absorption: potential impact on oral salt supplementation., Journal of Pharmaceutical Health Care and Sciences, 7(1):29 (2021).


10. Wen S, Arakawa H, Tamai I, CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages., Biochemical and Biophysical Research Communications, 581:6-11 (2021).

11. Kobayashi M, Mizutani A, Muranaka Y, Nishi K, Komori H, Nishii R, Shikano N, Nakanishi T, Tamai I, Kawai K, Biological Distribution of Orally Administered [ 123 I]MIBG for Estimating Gastrointestinal Tract Absorption., Pharmaceutics, 14(1):61 (2021).

2018 International Meeting on 22nd MDO and 33rd JSSX

第39回生体膜と薬物の相互作用シンポジウム

薬物動態学研究室
〒920-1192
石川県金沢市角間町