金沢大学 薬物動態学研究室

Review & Books (English)

  1. Kato Y., Tamai I. New aspects of transporter research: future may exist "beyond the transport". Preface, Drug Metab Pharmacokinet, 23 : 221-222 (2008).
  2. Sato M., Anzai N., Tamai I. Angiotensin II receptor blockers induce alteration of serum uric acid level via renal uric acid transporters, A review of the authors' current research, Gout Nucl Acid Res, 33: 149-161 (2009).
  3. Nakanishi T., Tamai I. Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy. J Pharm Sci, 100: 3731-3750 (2011).
  4. Nakanishi T., Tamai I. Genetic polymorphisms of OATP transporters and their impact on intestinal absorption and hepatic disposition of drugs. Drug Metab Pharmacokinet, 27: 106-121 (2012).
  5. Tamai I. Oral drug delivery utilizing intestinal OATP transporters. Adv Drug Deliv Rev,64: 508-514 (2012).
  6. Rostami-Hodjegan A., Tamai I., Pang K. S. Physiologically based pharmacokinetic (PBPK) modeling: it is here to stay! Biopharm Drug Dispos, 33: 47-50 (2012).
  7. Nakanishi T., Ross DD. Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression. Chin J Cancer, 31(2): 73-99 (2012).
  8. Tamai I. Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21). Biopharm Drug Dispos, 34: 29-44 (2013).
  9. Tamai I., Nakanishi T. Analysis of intestinal transporters In Transporters in drug discovery, development and use. pp.179-199, Eds. Sugiyama Y. and Steffansen B. Aaps Press/Springer, New York (2013).
  10. Tamai I. How should we handle decreased efficacy caused by DDI on transporters for drug absorption and target-tissue distribution, but not associated with toxicity? Drug Metab Pharmacokinet, 28: 451-452 (2013).
  11. Tamai I., Nakanishi T. OATP transporter-mediated drug absorption and interaction. Curr Opin Pharmacol, 13(6): 859-863 (2013)
  12. Nakanishi T, Tamai I. Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers. Biopharm Drug Dispos, 35:463-484 (2014).
  13. Nakanishi T, Tamai I. Interaction of drug or food with drug transporter in intestine and liver. Curr Drug Metab, 16: 753-764 (2015).
  14. Nakanishi T, Tamai I. Roles of organic anion transporting polypeptide 2A1 (OATP2A1/SLCO2A1) in regulating the pathophysiological actions of prostaglandins. AAPS J, 20(1):13 (2017).

2018 International Meeting on 22nd MDO and 33rd JSSX

第39回生体膜と薬物の相互作用シンポジウム

薬物動態学研究室
〒920-1192
石川県金沢市角間町